In the course of evaluating the optimal duration of bisphosphonate treatment the FDA found little benefit of treatment beyond 5 years. [1,2] Moreover, examination of studies where bisphosphonates ...

If you've been given a diagnosis of osteoporosis your doctor will probably prescribe a bisphosphonate, a class of drugs that helps preserve and build bone. Alendronate (Fosamax, Fosamax Plus D ...

Romosozumab vs bisphosphonate use was not linked to increased CVD risks among patients with osteoporosis, challenging past concerns over its cardiovascular safety.

On the other hand, denosumab users trended towards a 36% higher risk for a major adverse cardiovascular event (MACE) within the next 3 years than bisphosphonate users, though this didn't reach ...