Notably, bisphosphonates bind to hydroxyapatite in bone, where they are incorporated into the mineral matrix. Release of the drug from the bone mineral matrix requires bone resorption, and ...

If you've been given a diagnosis of osteoporosis your doctor will probably prescribe a bisphosphonate, a class of drugs that helps preserve and build bone. Alendronate (Fosamax, Fosamax Plus D ...

via bone remodeling, to prevent fracture. Long-term bisphosphonate treatment of postmenopausal osteoporosis is associated with reduction of bone turnover and might, therefore, have deleterious ...

Romosozumab vs bisphosphonate use was not linked to increased CVD risks among patients with osteoporosis, challenging past concerns over its cardiovascular safety.