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Orphan noncoding RNAs define cancer identity and enable blood-based monitoring
We knew we had something interesting with T3p, a single small RNA found in breast cancer but absent from normal tissue. After being described in 2018, this molecule took our team on a six-year journey ...
Prior to cell division, chromosomes are seemingly a jumbled mess. During cell division, parent cell chromosomes and their duplicates sort themselves out by condensing, becoming thousands of times more ...
“Our findings suggest a role for NSD2 in maintaining MM cell identity, with potential implications for future therapeutic strategies based on targeting of NSD2.” “Our findings suggest a role for NSD2 ...
All cells in the body contain the same DNA, but different cell types express different genes; skin cells express genes for the skin, liver cells express liver genes, and so on. This coordination is ...
Scientists at City of Hope have uncovered a gene called SMOC1 that plays a surprising role in the development of type 2 diabetes (T2D) by converting pancreatic cells that normally produce insulin into ...
A new study published in Nature Biotechnology shows that stem cell differentiation is linked to cellular structures called P-bodies, providing a potential means of controlling cell identity.
The adult mammalian heart bears limited regenerative capacity, resulting in the irreversible loss of cardiomyocytes post-cardiac injury, and often culminating in end-stage heart failure. Cardiomyocyte ...
With its fascinating ability to regrow entire limbs and internal organs, the Mexican axolotl is the ideal model for studying regeneration. Scientists have now found a factor that tells cells which ...
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