Planar cell polarity (PCP) signalling is a well-conserved developmental pathway regulating cellular orientation during development. An evolutionarily conserved pathway readout is not established and, ...

Caprine-like Generalized Hypoplasia Syndrome (SHGC) is an autosomal-recessive disorder in Montbéliarde cattle. Affected animals present a wide range of clinical features that include the following: ...

EPFL scientists discover that certain cell structures, the centrioles, could act as information carriers throughout cell generations. The discovery raises the possibility that transmission of ...

Centrioles, the barrel-shaped organelles best known for their role in cell division, may also put their stamp on early embryos. In a newly fertilized embryo, the centrioles that are present come ...

Cells contain various specialized structures - such as the nucleus, mitochondria or peroxisomes - known as "organelles''. Tracing their genesis and determining their structure is fundamental to ...

All life on earth depends upon the process of mitosis or cell division in which the chromosomal content of a cell is equally divided between two new cells. For mitosis to occur, the chromosomes in ...

Centrioles are cylindrical structures involved in the generation of microtubules—fibers inside of cells that form a network to provide structure and shape to cells and to mediate transport processes.

Scientists have discover that certain cell structures, the centrioles, could act as information carriers throughout cell generations. The discovery raises the possibility that transmission of ...

How cell division occurs and is coordinated with organismal development is subject of intense research interest, as is how this process malfunctions in the development of tumors. Researchers have been ...

The goal of my research is to understand the biogenesis of centrioles/centrosomes and primary cilia, and how defects in these processes affect mammalian cell physiology and evoke stress responses.