Microarray platforms provide a method for 'global' ChIP analysis, but direct sequencing of enriched fragments has proven a more effective means for determining locations of DNA-binding proteins ...

Users can benefit from the reduced background inherent in ChIP technology, which performs faster and is considerably simpler to use than traditional kits.

Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...

The Kushal Dey Lab focuses on developing machine learning models and computational pipelines that integrate genomic and epigenomic data from RNA-seq, ChiP-seq, Perturb-seq and spatial transcriptomic ...