Voltage-gated calcium channels swing open with passing action potentials, allowing calcium ions into the cell, and slide shut when the membrane depolarization has passed. Two papers this month suggest ...

Figure 1: Afterhyperpolarization at the calyx reduces the Prob AP at the axon. The afterhyperpolarization also occurred after trains at 10–20 Hz (20–100 action potentials; Fig. 1i), which could also ...

In the mammalian brain, synaptic transmission usually depends on presynaptic action potentials (APs) in an all-or-none (or digital) manner. Recent studies suggest, however, that subthreshold ...

Like thermostats that switch on heating or cooling to regulate temperature, neurons tune their excitability up or down to weather environmental changes. Who would have thought, though, that nerve ...