Chemotherapy drugs that target cancer cells without damaging normal cells remain one of the key goals of precision medicine ...

Acyl glucuronides represent a crucial class of metabolites generated through the glucuronidation of carboxylic acid-containing compounds. In the realm of drug metabolism, these conjugates are formed ...

Drug discovery is a high-risk, high-cost endeavor, with over 90% of candidates failing in clinical development. A significant proportion of these failures stem from unresolved biopharmaceutic ...

Neurodegenerative disorders are pressing global health challenges that stem from progressive neuronal dysfunction and loss. While the central roles of ...

This article is based on a poster originally authored by Daniel A. Barr, Mario Öeren, Peter A. Hunt, Jonathan D. Tyzack, Tomáš Chrien, Tamsin E. Mansley and Matthew D. Segall, which was presented at ...