The Albert and Mary Lasker Foundation announced that the 2016 Albert Lasker Basic Medical Research Award was shared by William Kaelin of the Dana-Farber Cancer Institute, Peter Ratcliffe of the ...

Randomized controlled trials have generally shown a benefit from accelerated radiotherapy in head and neck squamous cell carcinoma (HNSCC). However, the large randomized United Kingdom trial CHART ...

In the complicated, occasionally counter-intuitive world of signal transduction pathways, sometimes events turn out to be much simpler than first supposed. Such is the case with an important oxygen- ...

Clinical performance of Signatera Genome assay in a cohort of patients (pts) with solid tumors. Pooled mutation frequencies for all considered genes in different cancer types.

The efficacy and adverse event profiles of HIF-PHIs may differ among agents. Although all hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) target the HIF pathway, the individual ...