Huntington’s disease was long thought to be caused by the slow buildup of a toxic protein, but new research has revealed that it’s actually driven by the expansion of a gene that, at a certain ...

UCLA Health researchers say study findings uncover Huntington's disease mechanisms and pave new ways to develop treatments.

Huntington's disease is a genetic condition caused by an unusually long DNA sequence (CAG) in the huntingtin gene. In individuals with HD, this already extended sequence of CAGs continues to get ...

Study Finds Surprising Way That Genetic Mutation Causes Huntington's Disease, Transforming Understanding of the Disorder Jan. 16, 2025 — Scientists have discovered a surprising mechanism by ...

Thom Graves Media While genome sequencing may be the new ... honed on the rare single-gene disorders, such as Huntington disease (HD) and cystic fibrosis (CF), which dominated the field in the last ...

Craig Venter. For several years, Venter had been using automated DNA sequencers to sequence portions of chromosomes associated with Huntington's disease and myotonic dystrophy (Adams et al., ...

Huntington's disease is a rare genetic, autosomal dominant, neurodegenerative disease, caused by CAG repeat expansions in the ...

This debilitating, heritable condition is caused by >35 repeats of a trinucleotide sequence—a ... of ASOs for treating genetic conditions like Huntington’s disease is great, but there remain ...

Huntington's disease (HD) is a hereditary neurodegenerative ... of the caudate nucleus on brain imaging. Today, DNA testing can reliably diagnose HD and differentiate the disease from other disorders ...