Huntington's disease (HD) is an inherited neurodegenerative disease caused by an abnormal expansion of a CAG repeat in the huntingtin ( HTT) gene. The primary genetic determinant of the age at ...

Huntington's disease is a genetic condition caused by an unusually long DNA sequence (CAG) in the huntingtin gene. In individuals with HD, this already extended sequence of CAGs continues to get ...

Thom Graves Media While genome sequencing may be the new ... honed on the rare single-gene disorders, such as Huntington disease (HD) and cystic fibrosis (CF), which dominated the field in the last ...

Craig Venter. For several years, Venter had been using automated DNA sequencers to sequence portions of chromosomes associated with Huntington's disease and myotonic dystrophy (Adams et al., ...

Germline CAG-repeat expansions mean that the children of individuals with Huntington’s disease ... targets in human genetic and animal studies 4. Furthermore, the two-phase disease model ...

UCLA Health researchers say study findings uncover Huntington's disease mechanisms and pave new ways to develop treatments.

Study Finds Surprising Way That Genetic Mutation Causes Huntington's Disease, Transforming Understanding of the Disorder Jan. 16, 2025 — Scientists have discovered a surprising mechanism by ...

New research shows that the adult brain can generate new neurons that integrate into key motor circuits, findings that may point to a new way to treat neurogenerative disorders.

Huntington's disease (HD) is a hereditary neurodegenerative ... of the caudate nucleus on brain imaging. Today, DNA testing can reliably diagnose HD and differentiate the disease from other disorders ...