Obesity is not a single disease. New research shows distinct biological phenotypes that explain why weight gain and treatment ...

Insulin is one of the most potent and pleiotropic hormones in the body, regulating a myriad of physiological processes. However, perhaps none is best studied as its role in regulating glucose ...

Three years ago, the inceptor protein was discovered and its role as an inhibitor of the insulin signaling pathway was described. Inceptor and the insulin receptor are located on the surface of beta ...

Obesity has become a global epidemic affecting diverse populations and leading to metabolic syndrome across different sexes and age groups. A significant aspect of obesity is the development of leptin ...

In nerve cells, the hormone regulates whether mitochondria are shut down or kept running. The hormone insulin controls many cellular processes and adapts them to the body's current energy supply. One ...

A new study uncovers how endothelial cells contribute to insulin resistance in obesity-associated diabetes, highlighting adrenomedullin as a potential therapeutic target. Study: Endothelial insulin ...

Gut microbes produce a molecule that switches off inflammation linked to diabetes, offering a surprising new path to ...

Dietary choices and the gut microbiome likely play a large role in the development and management of type 2 diabetes. A recent study suggests that a certain microbial metabolite could help reduce ...