There are significant benefits to dry granulation, in terms of cost-reduction and processing, and it can be used with sensitive materials. However, there is little indication as to which process ...

Using a novel automated microfilling system, the authors demonstrate that roller compaction followed by milling is a viable preprocessing technique for high-dose chemical-in-capsule dosage forms. The ...

The authors evaluate the effect of various mill types on particle-size distribution, flowability, tabletability, and compactibility. The particle-size distribution of a pharmaceutical granulation is ...

Several challenges may be presented when processing powder blends: the blend may be prone to segregation, the creation of agglomerates may influence homogeneity, or component powders may poorly flow ...