The role of neuron and dopamine loss in Parkinson's Disease (PD) has long been recognized by neuroscientists. However, how dopaminergic modulation affects brain regions involved in the control of ...

Compared to other animal species, humans can plan and execute highly sophisticated motor tasks, including the ability to write complex characters using their hands. While many past studies have tried ...

A new study in mice has helped illuminate how the brain’s primary motor cortex (M1) – a brain region most commonly associated with control of motor functions – helps suppress dimensions of neuropathic ...

The neural network in the primary motor cortex transitions from a "beginner" state (light blue, left) to an "expert" configuration (dark blue, right). Dopamine release from the ventral tegmental area ...

A research team has revealed that a molecule in the brain -- ophthalmic acid -- unexpectedly acts like a neurotransmitter similar to dopamine in regulating motor function, offering a new therapeutic ...

The motor cortex homunculus is getting a makeover. New research has essentially redrawn the motor cortex and constitutes one of the most substantial shifts in our topographical knowledge of a sensory ...

A new study from researchers at the University of Chicago has found that neuronal population dynamics in the motor cortex are very different during reaching and grasping behavior, challenging a ...

A new study shows inhibiting the kinase p38α using the small molecule drug neflamapimod, could potentially improve cognitive and motor function in patients with neurodegenerative diseases that affect ...

A layer deep in the cerebral cortex, which is the innermost layer of the mammalian brain, has recently been found to play a role in the regulation of brain states associated with wakefulness and ...