A deep dive into the Fc–FcR axis as a therapeutic anchor in autoimmune disease, examining immune signaling and drug ...

Receptor tyrosine kinases (RTKs) regulate many critical biological processes such as cell growth, differentiation, and survival through the recruitment of intracellular signaling molecules. The ...

From studies conducted on animals, evidence has emerged that both neutralizing activity and Fc-mediated effector functions of neutralizing antibodies provide some levels of protection against the ...

A collaborative study on a plant intracellular immune receptor not only shows how an important resistance protein is activated during pathogen infection but also reveals some common operational ...

– Data provide insights on the signaling pathways involved with AK006 mast cell inhibition –– AK006 has a distinct mechanism of action that leads to broad inhibitory effects on mast cells – The ...

A synthetic protein has demonstrated the ability to discriminate between cancerous and non-cancerous cells in vitro, showing potential for advances in personalized treatments. Researchers from ...

Research teams explore the activation of plant immune receptors by pathogens. In a recent study, Alexander von Humboldt Professor Jijie Chai at the University of Cologne and his team together with ...

From the Riddell, Paulovich Labs, Clinical Research Division and Gottardo Lab, Vaccine and Infectious Disease Division. In order to identify why the different costimulatory domains have differing ...