Brain Changes in Huntington's Disease Decades Before Diagnosis Will Guide Future Prevention Trials Jan. 17, 2025 — Subtle changes in the brain, detectable through advanced imaging, blood and ...

Huntington’s Disease (HD) is a condition that stops parts of the brain working properly over time and is usually fatal. There is no treatment for HD and no cure. “This whole thing around ...

emerged decades before clinically diagnosable Huntington's disease. Approximately 23 years before a clinical diagnosis, CSF analysis showed very early signs of neurodegeneration with elevated NfL ...

HD is a rare, adult-onset, autosomal dominant, progressive neurodegenerative disease. George Huntington (Figure 1) was the first person to provide a comprehensive description of adult-onset HD in ...

Researchers from the Huntington's Disease Center, UCL Queen Square Institute of Neurology, and UK DRI at UCL have taken major steps forward in advancing MSH3-targeting therapies for Huntington's ...