The study of cancer genomics has revealed that both inherited (germline) and acquired (somatic) genetic variations significantly influence cancer ...

Cancer is driven mainly by genomic instability, manifesting through a spectrum of somatic mutations that range from single nucleotide substitutions to large-scale chromosomal rearrangements, which ...

Precision medicine in prostate cancer utilizes genetic testing to identify patients for PARP inhibitor treatment, enhancing personalized care. Genetic testing, including germline and somatic, is ...