Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src ...

T cell development is a tightly regulated process that transforms immature thymocytes into mature T cells with distinct functionalities. In the thymus, precursor cells undergo a series of selection ...

Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before ...

Learn how Logic-gated DARPins work to activate T cells selectively in solid tumours, enhancing therapeutic outcomes.

New findings could aid future development of more efficient therapeutic strategies in the context of regenerative medicine and aging.

Targeting receptors for erythropoietin on dendritic cells may be a viable strategy for treating MS and other diseases, ...

Automated TCR-T production streamlines personalized immunotherapy, reducing patient burden and improving engineered T cell quality.

One of the most exciting advances in cancer treatments in the past decade is the development of T cell immunotherapies, in which a patient's own immune system is trained to recognize and attack ...

A single signaling pathway controls whether immune cells attack or befriend cells they encounter while patrolling our bodies, ...

Neoantigen vaccines are at the forefront of cancer research, driving personalized immunotherapy and improving outcomes ...