The presence of tophi - crystal deposits of uric acid found on the surface of the joints or in the skin and cartilage - in people with gout can increase their risk of developing cardiovascular disease ...

December 26, 2011 — Maintaining serum urate levels at less than 6 mg/dL is necessary for clearing tophi and dissolving monosodium urate monohydrate crystals in gout, but once it has been achieved, ...

Patients with gout who receive 5 years of treat-to-target urate-lowering therapy achieve reductions in serum urate levels, ...

—AR882 demonstrated safe and efficacious long-term reduction of serum urate (sUA) levels and elimination of urate crystal deposition in a sub-analysis of gout patients from the Asia-Pacific region— ...

Please provide your email address to receive an email when new articles are posted on . One of the thrilling aspects of scientific discovery is that it can come from almost anywhere, and almost anyone ...

Gout has been a familiar disease since ancient times; evidence of it has even been found in dinosaur remains. 1 The disease is characterized by a disturbance in the metabolism of urate that causes ...

The advanced imaging method dual-energy CT (DECT) has been found to be a reliable measure of tophus size and composition in patients with gout, according to new research published in Journal of ...

Gout is a common type of inflammatory arthritis that causes sudden, severe pain, swelling and tenderness. It can affect any joint in the body including the feet, ankles, knees, hands, wrists, elbows ...

Gout is an inflammatory arthritis, which usually has a sudden onset of symptoms. It can affect any joint, but the small joint at the base of the big toe is the most commonly affected join that gets ...

“MSU crystals have impressive negative effects on the survival, function and differentiation of osteoblasts,” says Nicola Dalbeth, from the University of Auckland, New Zealand. These claims are based ...

This disease is characterised by sudden onset of intense joint pain, red and inflamed joints, tophi formation in the toes, heels, knees, fingers, ears, forearms, or even elbows. If not properly ...