USC enters as the betting favorite after a strong bounce-back season and an impressive recruiting haul, but laying 6.5 points may be a stretch. Several key contributors on both sides of the ball will be unavailable, narrowing the gap more than the market suggests.

Watch: Our Darren 'Doogie' Wolfson spoke with USC men's hoops coach Eric Musselman ahead of Friday night's game at the Barn vs. the Gophers. Bill, Eric's dad, led the Gophers to the 1972 Big Ten title.

The No. 2 Michigan Wolverines look to remain undefeated on Friday, Jan. 2 when they host the No. 24 USC Trojans.

Kickoff from the Alamodome in San Antonio, Texas is at 9 p.m. ET. The Trojans are 4.5-point favorites in the latest USC vs. TCU odds, while the over/under is 56.5. Before making any TCU vs. USC picks, check out the college football predictions from the SportsLine Projection Model .