Arginase deficiency is a rare autosomal recessive metabolic disorder that disrupts the final step of the urea cycle, impairing the conversion of arginine into urea and ornithine. In affected ...

Urea cycle disorders are congenital diseases that are caused by a dysfunctional urea cycle. The genetics and biochemistry of these disorders have been extensively studied. They are the result of a ...

A 25-year-old woman in Australia died after consuming too much protein, in the form of protein powder shakes, supplements and protein-packed foods, the New York Post reported yesterday. The woman, a ...

Researchers have revealed the presence of a functional urea cycle in the star-shaped cells of the Alzheimer's Disease (AD) brain. Key results point to the role of the urea cycle in amyloid-beta plaque ...

An Improved method of isolation and quantitation, using Dowex-1 ion-exchange chromatography and paper electrophoresis, has permitted efficient recovery of guanidinosuccinic acid from serum, urine and ...

What determines whether astrocytes play a beneficial or detrimental role in Alzheimer’s disease? It’s surely complicated, but a study in the June 10 online Cell Metabolism lays some of the blame on ...

The specific symptoms of disorders related to the urea cycle vary among the different types of these disorders. Typically, with complete deficiency of urea cycle enzymes, symptoms present within the ...

The number of elderly suffering from Alzheimer’s Disease has been rapidly rising over the past decades. For a long time, scientists believed that misfolded aggregates of amyloid-beta protein ...