The results uncover a notable parallel between the innate and adaptive immune systems. Whereas DNA deamination targeted to endogenous immunoglobulin loci is used to trigger the diversification of ...
In a phosphorylation-dependent positive feedback loop, the cytidine deaminase AID amplifies the generation of double-strand DNA breaks, which shows it can also function downstream of deamination. You ...
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is subjected to the host’s deamination system that includes the cytidine-to-uridine (C-to-U) deamination by apolipoprotein B messenger ...
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