Week 4 of college football brings more uniform heat with deep meanings. After losing to the Missouri Tigers in Week 3, who knocked them out of the AP Top-25 rankings, the Boston College Eagles are looking for vengeance Saturday when they take on the Michigan State Spartans.

Crowd noise was being pumped through the speakers to help the Spartans prepare for the next challenge, which will be Saturday night at Boston College. It will also serve as the annual “Red Bandanna Game” for the Eagles, honoring university alumnus Welles Crowther, a hero who died in the Sept. 11, 2001 terrorist attacks.

According to Boston College Athletics via social media, the Eagles Sept. 21 matchup against the Michigan State Spartans is officially sold out.

Free Press sports writer Chris Solari breaks down Michigan State's trip Saturday to Boston College to close out the Spartans' nonconference play.

Michigan State (3-0, 1-0 Big Ten) plays at Boston College (2-1, 1-0 ACC) on Saturday (8 p.m., ACC Network) to kick off a very difficult stretch of the schedule. Here are five things to watch in the game and a final score prediction:

If MSU can maintain a focused offensive strategy while cutting down on penalties, they have a chance to make this matchup competitive. Both teams have demonstrated a knack for putting points on the board, but MSU will need to execute effectively and convert key chances if they want to keep pace with BC's scoring.

The Michigan State Spartans (3-0) and Boston College Eagles (2-1) clash Saturday at Alumni Stadium. Kickoff is scheduled for 8 p.m. ET (ACC Network). Let's analyze BetMGM Sportsbook's

Michigan State football draws comments from Boston College coach Bill O'Brien on what he expects to see from the Spartans this Saturday along with the importance of the 11th Annual Red Bandana game.

Saturday, 8 p.m. ET (ACCN) Series record: Boston College leads 4-1-1. BetMGM College Football Odds: Boston College by 6½ WHAT’S AT STAKE? Boston College made a brief appearance at No. 24 in The Associated Press Top 25 after beating 10th-ranked Florida State in the opener and following it with a win over FCS Duquesne.

Michigan State is eager to hit the road against Boston College. Brad Galli shares the highlights With only 117 in MLB history, an immaculate inning is rarer than a no-hitter. MLB's first 50-50 season belongs to Shohei Ohtani.

If you've been watching MSU games on the Big Ten Network, Saturday's Boston College game will need to be seen somewhere else.