As if understanding this complex evolutionary puzzle were not ... Instead of the V(D)JC composition of immunoglobulin-based B cell receptors (BCRs) and T cell receptors (TCRs) in jawed vertebrates ...
but also determine a cell cycle state that enables RAG complex stability and V(D)J recombination. The pre-B-cell receptor (pre-BCR) is expressed following the productive recombination of the ...
A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from ... a mouse model of B-cell lymphoma called Eµ ...
Northwestern University researchers have identified structural features in engineered cell receptors ... the modeling of complex proteins, including single-pass transmembrane receptors.
Type-1 interferons regulate immune responses and the production of self-reactive antibodies that target red blood cells in a SCD mouse model.