BMJ2d
Postural instability/gait disturbance in Parkinson's disease has distinct subtypes: an exploratory analysis
Objective To test the hypothesis that postural instability with falling (PIF) and freezing of gait (FOG) are distinct subtypes of the postural instability/gait disturbance (PIGD) form of Parkinson's ...
BMJ12d
Ultra-high-dose methylcobalamin in amyotrophic lateral sclerosis: a long-term phase II/III randomised controlled study
Objective To evaluate the efficacy and safety of intramuscular ultra-high-dose methylcobalamin in patients with amyotrophic lateral sclerosis (ALS). Methods 373 patients with ALS (El Escorial definite ...
BMJ13d
Complete Epstein-Barr virus seropositivity in a large cohort of patients with early multiple sclerosis
Objective To determine the prevalence of antibodies to Epstein-Barr virus (EBV) in a large cohort of patients with early multiple sclerosis (MS). Methods Serum samples were collected from 901 patients ...
BMJ4d
The Tolosa-Hunt syndrome
aDepartment of Ophthalmology, University of Alabama School of Medicine, 601 700 South 18th Street, Birmingham, Alabama, USA, bNeuro-ophthalmology Unit, University of California School of Medicine, San ...
BMJ2d
N18 in median somatosensory evoked potentials: a new indicator of medullary function useful for the diagnosis of brain death
Dr Masahiro Sonoo, Department of Neurology, Teikyo University School of Medicine, Kaga 2–11–1, Itabashi-ku, Tokyo 173, Japan. Telephone 0081 3 3964 1211 ext 1911; fax 0081 3 3964 6397; email sonoom{at ...
BMJ12d
Deep brain stimulation activation volumes and their association with neurophysiological mapping and therapeutic outcomes
Dr C C McIntyre, Department of Biomedical Engineering, Cleveland Clinic Foundation, 9500 Euclid Ave ND20, Cleveland, OH 44195, USA; mcintyc{at}ccf.org Objective: Despite the clinical success of deep ...
BMJ9d
Disability after severe head injury: observations on the use of the Glasgow Outcome Scale.
The nature of the neurological and mental disabilities resulting from severe head injuries are analysed in 150 patients. Mental handicap contributed more significantly to overall social disability ...
BMJ4d
Hippocampal subfield atrophy of CA1 and subicular structures predict progression to dementia in idiopathic Parkinson’s disease
Background Global hippocampal atrophy is a hallmark of Alzheimer’s dementia and has been similarly reported in Parkinson’s disease dementia (PDD). However, there is limited literature on the ...
BMJ11d
Cognitive and behavioural changes in PLS and PMA:challenging the concept of restricted phenotypes
Correspondence to Dr Michael A van Es, Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht 3584 CX, The Netherlands; M.A.vanEs{at}umcutrecht.nl Objectives ...
BMJ3d
Cigarette smoking and risk of intracranial aneurysms in middle-aged women
Background and purpose We previously reported a single-centre study demonstrating that smoking confers a six-fold increased risk for having an unruptured intracranial aneurysm (UIA) in women aged ...
BMJ10d
Are men at greater risk for Parkinson’s disease than women?
1 Department of Neurology, University of Virginia School of Medicine, Charlottesville, USA 2 Department of Health Evaluation Sciences, University of Virginia School of Medicine Correspondence to: Dr G ...
BMJ3d
Effectiveness of early cycles of fast-acting treatment in generalised myasthenia gravis
Background Early fast-acting treatment (EFT) is the aggressive use of fast-acting therapies such as plasmapheresis, intravenous immunoglobulin and/or intravenous high-dose methylprednisolone (IVMP) ...