Dealbreaker on MSN9d
Beam Base Editor’s Early Data in Rare Liver Disease Tee Up $500M Stock Sale in Tough Market
A Beam Therapeutics gene-editing therapy designed to fix a mutation at the root of a rare liver protein deficiency now has ...
Nature12y
DNA Is Constantly Changing through the Process of Mutation
Consequently, the mutant protein is entirely different due to the deletion of the fourth nucleotide, and it is also shorter due to the appearance of a premature stop codon. This mutant protein ...
Hosted on MSN1mon
Leveraging a novel protein tagging strategy offers new route to cancer treatment
By creating a special compound that binds FBXW7-R465C, the Northwestern team was able to direct this mutant protein to accelerate degradation of other tumor-promoting proteins. Only the mutated ...
PBS8y
A Mutation Story:
Every person has two copies of the hemoglobin gene. Usually, both genes make a normal hemoglobin protein. When someone inherits two mutant copies of the hemoglobin gene, the abnormal form of the ...
Managed Healthcare Executive6d
First Clinical Proof of Genetic Mutation Correction for Rare Lung Disease
Early research shows a one-time gene therapy has potential for addressing both the liver and lung disease that patients with ...
EurekAlert!2d
Fudan team develops a novel CRG-based classification model for IDH1-mutant gliomas, advancing precision therapy optimization
A recent study published in MedComm – Future Medicine by a research team from Fudan University provides an in-depth ...
Beam Therapeutics: Single-Base Editing Seems To Work
The author is looking forward to seeing how Beam Therapeutics would do in their clinical trials of single-base DNA editing.
Cure Today24d
Zongertinib Receives Priority Review For HER2 Mutant NSCLC
Zongertinib, an investigational treatment for HER2-mutant advanced NSCLC ... Human epidermal growth factor receptor 2 (HER2): a protein on the surface of some cancer cells that, when overexpressed, ...