HD is a rare, adult-onset, autosomal dominant, progressive neurodegenerative disease. George Huntington (Figure 1) was the first person to provide a comprehensive description of adult-onset HD in ...

Since the first description in 1872 (ref. 1) of Huntington's disease—a hereditary neurodegenerative disease characterized by progressive movement disorder, cognitive decline and psychiatric ...

New research shows that the adult brain can generate new neurons that integrate into key motor circuits, findings that may ...

New research shows that the adult brain can generate new neurons that integrate into key motor circuits. The findings demonstrate that stimulating natural brain processes may help repair damaged ...

This type of medication can help manage the uncontrolled movements that can occur with Huntington’s disease. Huntington’s disease is a neurodegenerative disorder that causes a progressive ...

Mouse studies demonstrated that newly generated neurons connect with brain networks responsible for motor control.

Huntington's disease is one of the most common inherited ... or moderately (Msh2 and Mlh1) modify pathogenesis in HD mouse model. Interestingly, these genes together encode a minor mismatch ...