San Francisco 49ers head coach Kyle Shanahan had hoped to derail the Detroit Lions' quest for the NFC's top seed. A Monday ...

The Detroit Lions have revenge on their minds in a road game against the San Francisco 49ers. We give you the latest game ...

Lions, the NFL Week 18 schedule and more. More: NFL Week 17 winners, losers: Colts flame out in epic fashion with ...

Detroit Lions cornerback Amik Robertson turned down a lucrative free-agent offer from the San Francisco 49ers last offseason.

That's no minor accomplishment. The North is the best division in football, with three teams that will finish with more than 11 wins for the first time since the AFC East in 1985. Vikings-Lions will ...

The Lions (13-2) are looking to continue their winning ways against the 49ers (6-9) and keep their spot at the top of the NFC ...

The Detroit Lions will travel to San Francisco to take on the 49ers in the Week 17 Edition of NFL Monday Night Football. Two ...

The Lions have already defeated the Vikings once this season at U.S. Bank Stadium. If Detroit wins again, they're in based on ...

The Lions and 49ers kick off tonight at 5:15 p.m. PT (8:15 p.m. ET) on ABC, ESPN and ESPN Plus. Looking for the ManningCast?

Jay Croucher, Connor Rogers and Lawrence Jackson give their favorite bets for the Monday night matchup between Detroit and ...