We focus on the questions of how signals cross membranes, and how membrane proteins and membrane channels work at the level of atomic structure. We also focus on how the signal recognition particle (SRP) directs membrane and secreted proteins to the membrane.

AcrIF11 is a potent CRISPR-specific ADP-ribosyltransferase encoded by phage and plasmid. bioRxiv. 2024 Aug 26. Chen DF, Roe LT, Li Y, Borges AL, Zhang JY, Babbar P, Maji S, Stevens MGV, Correy GJ, Diolaiti ME, Smith DH, Ashworth A, Stroud RM, Kelly MJS, Bondy-Denomy J, Fraser JS. PMID: 39253479; PMCID: PMC11383003.

Professor, Dept. of Biochemistry & Biophysics and Dept. of Pharmaceutical Chemistry, UCSF [email protected] Phone: (415) 476-4224 (office)<br>(415) 514-4179 (asst)

Molecular cloning, expression, site-directed mutagenesis, and strong focus onto biochemistry are a key part of the arsenal for defining molecular mechanisms. We focus on the questions of …

‪Professor of Biochemistry and Biophysics, University of California in San Francisco‬ - ‪‪Cited by 43,590‬‬ - ‪structural biology‬ - ‪biochemistry‬ - ‪biophysics‬ - ‪transporters membrane...

In 1976 he was hired at the University of California, San Francisco to help establish a program in structural biology. At UCSF he used the Pacific electric ray, a model organism, to research the acetylcholine receptor that enables rapid signaling in the nervous system. [1]

Structural biology aimed at determining optimal therapeutic strategies, and fundamental mechanisms. Neurobiology and synaptic vesicles for quantal release of neurotransmitters.

The Stroud Lab is researching a variety of topics to help understand molecular mechanisms of certain key biological processes. To find out more about what specifically we are seeking to understand, please use the pull-down menu below or browse by scrolling down. Topics are listed from most current.

Robert Stroud is Professor of Biochemistry and Biophysics, at the University of California in San Francisco (UCSF). He is a structural biologist recognized for discovery of new paradigms in membrane protein biology including mechanisms of aquaporins, Rh factors, membrane protein synthesis and protein insertion through translocons, unfolded ...